The C/EBP-Beta Anti-Human Antibody (clone 47A1) from IBL- America is a Mouse Monoclonal antibody to CEBPB. This antibody recognizes Homo Sapiens, and Human antigen. The C/EBP-Beta Anti-Human Antibody (clone 47A1) has been validated for the following applications: EIA, Immunoassay, ELISA, and Western Blot.
Description
CCAAT/enhancer-binding proteins (C/EBPs) are a family of basic leucine zipper (bZIP) DNA binding proteins that play important roles in normal cellular differentiation and function in a variety of tissues. The C/EBP family is critical for innate immunity and inflammatory response, and consists of five core members: C/EBPalpha, C/EBPbeta, C/EBPdelta, C/EBPepsilon, and C/EBPgamma. Among these proteins, C/EBPbeta is usually highly expressed in liver, intestine, lung and adipose. C/EBPbeta has three isoforms, two activator, (LAP* and LAP) and a repressor (LIP). These isoforms are differentially translated from the same mRNA. The expression of these isoforms is developmentally and hormonally regulated